Published a new study on Dual Inhibitors of AChE and BACE-1 for Reducing Aβ in Alzheimer’s Disease: From In Silico to In Vivo

By applying the computational methods in order to search for dual-inhibitors that could prevent the production of hazardous Aβ42 peptides and avoid their aggregation, it was developed molecules which inhibit AChE and BACE-1 enzymes, while the most potent molecule shows a reduction in brain tissue of soluble Aβ42 in mice.

The publication can be accessed under the following link.